Amyotrophic lateral sclerosis
Trovati 12 articoli
- Neurodenegerative diseases: role of transport proteins
- Hampering the transport of proteins within cells may underlie several adult-onset neurodegenerative diseases, such as Huntington's, amyotrophic lateral sclerosis ( ALS ) and Kennedy disease. Understanding how this cell transport is blocked in these diseases may offer targets for future therapy.... (Leggi Articolo)
- Abnormal cell division associated with Alzheimer's disease
- A study in mice suggests that Alzheimer's disease may be triggered when adult neurons try to divide. The study is published in in The Journal of Neuroscience. For unknown reasons, neurons affected by Alzheimer's disease and many other neurodegenerative diseases often start to divide before... (Leggi Articolo)
- Mechanism that causes cell death in neurodegenerative disease
- Misfolded and damaged proteins are common to all human neurodegenerative diseases. Clumps of these aggregated proteins destroy neurons within the brain and cause disease. But explanations for the mechanism that actually causes cell death have varied widely, puzzling scientists and leading them to... (Leggi Articolo)
- Abraham Lincoln might have suffered from movement disorder
- Researchers at Johns Hopkins and the University of Minnesota have discovered a gene mutation in the descendants of Abraham Lincoln's grandparents that suggests the Civil War president himself might have also suffered from a disease that destroys nerve cells in the cerebellum -- the part of the br... (Leggi Articolo)
- Immune cells help to maintain cognition and brain cell renewal
- A team of researchers at the Weizmann Institute of Science, led by Michal Schwartz of the Neurobiology Department, has come up with new findings that may have implications in delaying and slowing down cognitive deterioration in old age. The basis for these developments is Schwartz's team's obs... (Leggi Articolo)
- Neurodegenerative diseases: Minocin protects brain and nerve cells from damage
- Researchers at the San Francisco VA Medical Center ( SFVAMC ) have identified the mechanism by which Minocycline ( Minocin ), a medication currently being studied for the treatment of neurodegenerative diseases including Parkinson's disease and Huntington's disease, protects brain and nerve cells... (Leggi Articolo)
- Mutations in the protein beta-III spectrin linked to spinocerebellar ataxia type 5
- Researchers at the University of Minnesota Medical School have discovered the gene responsible for a type of ataxia, an incurable degenerative brain disease affecting movement and coordination. This is the first neurodegenerative disease shown to be caused by mutations in the protein beta-III... (Leggi Articolo)
- Amyotrophic lateral sclerosis: exercise plus gene therapy shows promise
- A study in mice gives hope that a combination of gene therapy and exercise may extend the lives of people who have Lou Gehrig's disease. Amyotrophic lateral sclerosis ( ALS ), or Lou Gehrig's disease, is a chronic and progressive illness that leads to paralysis and ultimately death. There are ... (Leggi Articolo)
- Minocin might help alleviate HIV-induced neurological problems
- By studying animals, Johns Hopkins researchers have discovered that the antibiotic Minocycline ( Minocin ) might help alleviate HIV's negative effects on the brain and central nervous system, problems that can develop even though antiretroviral therapy controls the virus elsewhere in the body. ... (Leggi Articolo)
- Progressive aphasia syndrome linked to prion gene
- Most people with a rare type of dementia called primary progressive aphasia ( PPA ) have a specific combination of prion gene variants. The study, published in the Annals of Neurology, is the first to link the prion protein gene to this disorder. The researchers, led by James A. Mastrianni,... (Leggi Articolo)
- Protein aggregates in Lou Gehrig's disease linked to neuron death
- French neurologist Jean-Martin Charcot first described amyotrophic lateral sclerosis ( ALS ) in 1869, but, nearly 140 years later, little is known about the cause of the devastating neurodegenerative disease, and there is no cure. What is known about Lou Gehrig's disease, as it is commonly ca... (Leggi Articolo)
- Steps required to integrate new neurons into adult brain discovered
- In experiments with mice, researchers from Johns Hopkins' Institute for Cell Engineering ( ICE ) have discovered the steps required to integrate new neurons into the brain's existing operations. For more than a century, researchers thought the adult brain could only lose nerve cells, not gain ... (Leggi Articolo)
